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On the surface Adam (Mark Ruffalo), an over-achieving environmental consultant, Mike (Tim Robbins), a long-married small-business owner, and Neil (Josh Gad), a wisecracking emergency-room doctor, have little in common. But all are in different stages of dealing with addiction. Confident and successful in his career, Adam is afraid to allow love back into his life, even if that means losing a chance to start over with smart, beautiful and accomplished Phoebe (Gwyneth Paltrow); Mike's efforts to control his wife, Katie (Joely Richardson), and son, Danny (Patrick Fugit), as tightly as he does his impulses are tearing the family apart; and Neil is still deeply in denial when befriended by Dede (Alecia Moore), who has just begun to take her own small steps back to health. As they navigate the rocky shores of recovery, Adam, Mike and Neil become a family that encourages, infuriates and applauds each other on the journey toward a new life.

A comedy that follows three sex addicts as they struggle to function in society while maintaining meaningful relationships. Along the way, Adam (Ruffalo) attempts to forge a relationship with Phoebe (Paltrow), a wildly independent and beautiful woman who has sworn off dating addicts after breaking up with an alcoholic. Mike (Robbins) is married to his high school sweetheart, but becomes as addicted to his 12 step recovery program as he does to sex. Neil(Gad), on the other hand, hides a camera on his tennis shoe to secretly film up women's skirts – all while trying to convince his friends that he can live a life without sex. Throughout the film, they each deal with their addictions in different and hilarious ways in this unusual and sweet comedy.