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In the not-so-distant future when an epidemic of organ failures devastates the planet, scientists gear for a massive organ harvest. A biotech giant comes up with easy organ payment plans, but all financed organs are subject to legal default, including repossession at the hands of repo men.
A road trip to the biggest college football championship of the year takes a turn for the worse for Carly, Paige and their friends, when they decide to camp out for the night before heading to the game. A confrontation with a mysterious trucker at the camp site leaves everyone unsettled, and Carly has her hands full trying to keep the peace between her boyfriend Wade and her hot-headed brother Nick. They wake up the next morning to find that their car might have been tampered with, preventing their departure. At the risk of being stranded, they accept a local's invitation for a ride into Ambrose, the only town for miles. Once there, they are drawn to Ambrose's main attraction--Trudy's House of Wax, which is filled with remarkably life-like wax sculptures. But as they soon discover, there is a shocking reason the exhibits look so real. As the friends uncover the town's dark secrets, they are stalked by a mysterious killer and find themselves in a bloody battle for survival. The group must find a way out of Ambrose—or become permanent additions to the "House of Wax".