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The story centers on an opera singer (Brittany Murphy) who seeks out the services of Sigmund Freud in post-World War I Vienna. Haunted by hallucinatory dreams about a white hotel, she becomes Freud's famous case study Anna G. Together, they unlock the key to figuring out her memories and her premonitions of the future, which include the Holocaust.
The film is set in 1965, the year Sedgwick met Andy Warhol and became known as his muse and later died of a barbiturate overdose in 1971 at the age of 28.