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Story centers on Marco Polo, a Venice merchant, who served as an ambassador to the empire of Kublai Khan as he traveled with his father and uncle through a war-torn Asia.
In the early 1990s, a Johnson & Johnson pharmaceutical rep helps sell the anti-anemia drug Procrit until he comes to believe it is causing harm. The salesman, who works in Johnson & Johnson's new biotech division, is fired from the pharmaceutical company after warning that the drug he had championed is dangerous. Attorney Jan Schlichtmann takes on the case for the sales rep and the plaintiffs.