My Sister's Keeper Movie Cast, Plot and Everything to Know

Plot

What's the story about?

Plot

Sara and Brian Fitzgerald's life with their young son and their two-year-old daughter, Kate, is forever altered when they learn that Kate has leukemia. The parents' only hope is to conceive another child, specifically intended to save Kate's life. For some, such genetic engineering would raise both moral and ethical questions; for the Fitzgeralds, Sara in particular, there is no choice but to do whatever it takes to keep Kate alive. And what it takes is Anna.

Kate (Sofia Vassilieva) and Anna (Abigail Breslin) share a bond closer than most sisters: though Kate is older, she relies on her little sister--in fact, her life depends on Anna.

Throughout their young lives, the sisters endure various medical procedures and hospital stays--just another part of their close-knit family's otherwise normal life. Sara (Cameron Diaz), a loving wife and mother who left her career as an attorney to care for her daughter, is sometimes lost inside the single-minded caregiver she has become in her efforts to save Kate. Her strong, supportive husband, Brian (Jason Patric), is often rendered powerless and passive by his wife's strength and determination. And their only son, Jesse (Evan Ellingson), drifts, at times all but forgotten as Kate and Anna take center stage.

Until Anna, now 11, says "no." Seeking medical emancipation, she hires her own lawyer (Alec Baldwin), initiating a court case that divides the family and that could leave Kate's rapidly failing body in the hands of fate.

Drama

Top Cast

The lead cast starring in My Sister's Keeper.

• 
  Cameron Diaz

  Shrek 5, Back In Action

• 
  Abigail Breslin

  Classified, Ender's Game

• S
  Sofia Vassilieva

  13 Minutes, Other People’s Children

• J
  Jason Patric

  Armor, Cavemen

• 
  Alec Baldwin

  Clear Cut, Three Mississippi

• J
  Joan Cusack

  Toy Story 4, Mars Needs Moms!

• 
  Thomas Dekker

  Foreverland, Do You Take This Man

• E
  Evan Ellingson

Crew Behind the Film

The My Sister's Keeper behind-the-scenes crew and production team.

The film's director Nick Cassavetes last directed Marked Men: Rule & Shaw and God is a Bullet. The film's writer Jeremy Leven last wrote Girl On a Bicycle and Real Steel.

Director

Nick Cassavetes

Screenwriter

Jeremy Leven

Producers

Scott Goldman
Mark Johnson
Chuck Pacheco
Hillary Sherman

Production Details

What we know about the My Sister's Keeper movie production.

Key Facts

• Based on the bestselling book from Jodi Picoult, "My Sister's Keeper" reveals surprising truths that challenge one's perceptions of family love and loyalty and give new meaning to the definition of healing. Dakota and Elle Fanning were originally set to play the Fitzgerald sisters but Dakota changed her mind when she found out she would have to shave her head to play the leukemia-suffering character of Kate. Elle dropped out along with her sister, and they were replaced with Sofia Vassilieva and Abigail Breslin.

Production Updates for My Sister's Keeper

Jun 2009

Completed

Changed My Sister's Keeper movie production status. The movie is ready for release.

Nov 2008

Production

Changed the movie production status to Production. The movie is currently being filmed.

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Additional Information

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