In a world hit by a wave of mutations that are gradually transforming some humans into animals, François (Romain Duris) does everything he can to save his wife, who is affected by this mysterious condition. As some of the creatures disappear into a nearby forest, he embarks with Emile (Paul Kircher), their 16-year-old son, on a quest to find her with some help from a local police officer (Adèle Exarchopoulos).
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