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Brian O'Conner (Paul Walker), stripped of his badge after the events of the first film, gets a chance to redeem himself by going undercover to infiltrate the world of Miami street racing.
A virus that locks those infected into a permanent state of killing rage, is accidentally released from a British research facility. Carried by animals and humans, the virus is impossible to contain, and spreads across the entire planet. Twenty-eight days later, a small group of survivors are trapped in London, caught in a desperate struggle to protect themselves from the infected. As they attempt to salvage a future from the apocalypse, they find that their most deadly enemy is not the virus, but other survivors.
From the Mexican writing-directing team behind the Oscar-nominated "Amores Perros" comes this explosive, emotionally charged English-language drama about a woman (Naomi Watts), her cheating lover (Sean Penn), and an ex-convict (Benicio Del Toro).