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Dee Dee Allen (three-time Academy Award winner Meryl Streep) and Barry Glickman (Tony Award winnerJames Corden) are New York City stage stars with a crisis on their hands: their expensive new Broadway show is a major flop that has suddenly flatlined their careers. Meanwhile, in small-town Indiana, high school student Emma Nolan (newcomer Jo Ellen Pellman) is experiencing a very different kind of heartbreak: despite the support of the high school principal (Keegan-Michael Key), the head of the PTA (Kerry Washington) has banned her from attending the prom with her girlfriend, Alyssa (Ariana DeBose). When Dee Dee and Barry decide that Emma's predicament is the perfect cause to help resurrect their public images, they hit the road with Angie (Academy Award winner Nicole Kidman) and Trent (Andrew Rannells), another pair of cynical actors looking for a professional lift. But when their self-absorbed celebrity activism unexpectedly backfires, the foursome find their own lives upended as they rally to give Emma a night where she can truly celebrate who she is.
Esther Gold (Glenn Close) devotes herself to her comatose, bedridden son, and expresses love for her daughter by trying to win her a car in a last-one-standing radio contest. Jim Train (Dermot Mulroney) questions his value as a man when he is passed over for promotion; Annette Jenning (Patricia Clarkson) tries to keep her family intact in the wake of her divorce; and Helen Christianson (Mary Kay Place) looks for fun and inspiration in her banal life. Despair and humor are delicately balanced in this film that examines people's investment in things that are more predictable, if less satisfying, than their relationships with other people.