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The story of Issac Bruno (Adams), as astronomer obsessed with searching the cosmos for signs of life beyond Earth, despite the collapse of his own personal life around him. Isaac takes on an unqualified but spirited young research assistant named Clara (Bellisario) who restores balance and perspective in the midst of his downward spiral.
Years after the shocking murders that made the name Charles Manson synonymous with pure evil, the three women who killed for him—Leslie Van Houten (Hannah Murray), Patricia Krenwinkel (Sosie Bacon), and Susan Atkins (Marianne Rendón)—remain under the spell of the infamous cult leader (Matt Smith). Confined to an isolated cellblock in a California penitentiary, the trio seem destined to live out the rest of their lives under the delusion that their crimes were part of a cosmic plan—until empathetic graduate student Karlene Faith (Merritt Wever) is enlisted to rehabilitate them.
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