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When the owner of a Baltimore working class convenience store, Sylvia Stickles (Tracey Ullman), suffers a concussion, the injury causes a drastic change in her sexual drive, turning her into a sex addict with crazy, wild and urgent desires and compulsions, much to the joy and then frustration of her husband (Chris Isaak) who has trouble keeping up with her, as her new personality threatens to tear apart the remnants of what wasn't an entirely perfect family to begin with.