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An "expendable" person is sent on the most dangerous, even suicidal jobs. When an expendable dies, a new body is regenerated with most of the memories intact. Essentially, Mickey7 is the seventh iteration of an expendable who is undergoing an existential identity crisis while trying to keep his successor's regeneration a secret and negotiating with the planet's native species on a dangerous trip to colonize a new ice world.
Max has lived a mundane life as a cab driver for twelve years. The faces have come and gone from his rear-view mirror: people and places he's long since forgotten—until tonight. Vincent is a contract killer. When an off-shore narco-trafficking cartel learns that they're about to be indicted by a federal grand jury, they mount an operation to identify and kill the key witness, and the last stage is tonight. It is on this very night that Vincent has arrived—and five bodies are supposed to fall. Circumstances cause Vincent to hijack Max' taxicab, and Max becomes collateral—an expendable person who's in the wrong place at the wrong time. Through the night, Vincent forces Max to drive him to each assigned destination. And as the L.A.P.D. and F.B.I. race to intercept them, Max and Vincent's survival become dependent on each other, in ways neither would have imagined.