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In a continuation of the epic story, Dr. Kelson (Ralph Fiennes) finds himself in a shocking new relationship - with consequences that could change the world as they know it - and Spike's (Alfie Williams) encounter with Jimmy Crystal (Jack O'Connell) becomes a nightmare he can't escape. In the world of The Bone Temple, the infected are no longer the greatest threat to survival - the inhumanity of the survivors can be stranger and much more terrifying.

Columbus (Jesse Eisenberg) has made a habit of running from what scares him. Tallahassee (Woody Harrelson) doesn't have fears. If he did, he'd kick their ever-living ass. In a world overrun by zombies, these two are perfectly evolved survivors. But now, they're about to stare down the most terrifying prospect of all: each other.