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Ray Keene (Cusack), a father who wants to redeem himself in the eyes of his son, is trying to bring Cordell (Freeman), a world-class assassin to justice. All the while, he must protect his son and evade the assassin's team who are methodically hunting them down in the wilderness.
Inspired by "Cujo" and "The Birds", "The Breed" follows five young friends who vacation on a peaceful deserted island only to discover that the canines they befriend are genetically altered and possess a frighteningly high level of intelligence -- with an appetite to match.