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Anna Fox lives alone in the New York City brownstone that once housed her happy family. She suffers from agoraphobia and is separated from her husband and daughter. She spends her days chatting online with strangers, watching old movies, drinking to excess and spying on her neighbors. This gets interesting when the Russell clan moves in next door. Watching the bond between the parents and their teen son makes her long for her own reunion with her own family, but that changes when she observes what seems to be a shocking act of violence. The housebound woman must confront what she saw, or whether she has become unhinged.
Set in a retro-futuristic past, an orphaned teenager (Millie Bobby Brown) traverses the American West with a sweet but mysterious robot and an eccentric drifter (Chris Pratt) in search of her younger brother.
When his pregnant wife is kidnapped and held as collateral, Paul, an ER nurse, must team with the badly injured career criminal and murder suspect under his charge in order to save the lives of his wife and unborn child. Pitted against rival gangs and a deadly ring of corrupt cops, the unlikely duo find a way to survive together in the fight of their lives.