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Matthew Broderick will play a man who suffers from some memory loss after suffering a knock on the head. He takes a trip with his uncle (Alan Alda), who suffers from Alzheimer's, and high school sweetheart (Virginia Madsen) to a memorabilia show where they will try to sell a rare baseball card.
Izzy is an 11-year-old boy living in New York City who spends his time breaking into people's apartments to "mess with them," creating his own private world that is more controlled and stable than the reality of his family's lives, as his mother (Mary-Louise Parker) struggles with the hardship of her husband's recent stroke while also dealing with the difficulties of raising three children.